2023-01-10 10:45:00
Sunshine Vitamin to Stay Fit
A Vitamin-D deficiency is a global health issue and is one of the most common nutrient deficiencies. India gets surplus sun, yet a large percentage of Indians suffer from significant vitamin D deficiency. More than seven out of ten Indians lack in vitamins, and most of them suffer from vitamin D deficiency. The prevalence of Vitamin D deficiency in India ranged from 40% to 99%, with most of the studies reporting a prevalence of 80%–90%.It is prevalent in all the age groups and high-risk groups alike.
Ultraviolet B Radiation
Vitamin D is produced by skin
exposed to ultraviolet B radiation or obtained from dietary sources, including
supplements.Persons commonly at risk for vitamin D deficiency include those
with inadequate sun exposure, limited oral intake, or impaired intestinal
absorption.
Vitamin Disorder
Vitamin-D deficiency has been associated with
rickets, osteomalacia, osteoporosis, as well as fetal development, immune
system function, neurological disorder such as multiple sclerosis,cancer, and
many other pathologies.
Diagnosis & Montioring – 25
HYDROXYVITA D (25-Hydroxyvitamin D Concentration in
the blood)
Measuring accurate level of Vitamin- D
in patients is very important for the diagnosis of Vitamin-D deficiency and for
the monitoring of deficient patients to achieve optimal levels.Vitamin D adequacy is best determined by measurement of the
25-hydroxyvitamin D concentration in the blood.
Test In Market:ELISA),
chemiluminescence
immunoassay and protein binding assays are used in routine testing of 25(OH)D
in clinical laboratories. LCTMS (liquid chromatography tandem mass
spectrometry) is the widely accepted reference method for 25(OH)D measurement.
However, LCTMS is tedious, expensiveand time consuming and therefore seldom
used commercially.
ELISA
Kit
ELISA method is commonly used to
quantify the 25-hydroxyvitamin D
concentration in the blood in
clinical laboratories.
TRUSTwell – Vitamin D (Total) ELISA Kit can quantify total 25(OH) Vitamin D
in human serum and comes with the
following perks & benefits to the customers.
_ Accuracy : R2 = 0.918 with CLIA as reference
_ Analytical Sensitivity: 1.2 ng/mL
_ Specificity: No cross reactivity to non-hydroxylated vitamin D2
and Vitamin D3
_ Calibrator range: 0-150 ng/mL
_ Intra & Inter assay precision : CV <=10%
_ Higher linearity: 0-150 ng/mL
_ 1 step less procedure, faster resulting
_ High & Low level assay controls